India has one of the highest rates of micronutrient deficiency in the world — and the supplement market is growing fast to meet it. But with hundreds of products on Amazon.in and little regulation, knowing what to actually buy is harder than it should be. This guide covers ASU from first principles: what it is, what the evidence says, and how to use it safely in an Indian context.
What is ASU?
ASU (avocado-soybean unsaponifiables) is a proprietary extract of avocado and soybean oils, standardized to approximately
ASU is relevant for anyone dealing with knee-pain. It primarily acts on the knees.
How does ASU work?
ASU appears to stimulate collagen synthesis in chondrocytes while inhibiting cartilage-degrading enzymes (matrix
Who should take ASU?
Adults with knee osteoarthritis seeking a supplement with both symptomatic and structural benefits. Particularly relevant
The typical dose is 300 mg of ASU daily (standardized to ~100 mg avocado unsaponifiables + 200 mg soybean unsaponifiables). Once daily, typically with breakfast.
Safety and who should avoid it
Avoid if you have a soy or avocado allergy. Use caution with anticoagulant medications. Not for pregnancy or breastfeeding.
Always consult your doctor before starting any new supplement, particularly if you are on prescription medication or have an existing health condition.
How to combine ASU
ASU works well alongside calcium d glucarate. The Ayurvedic tradition has long used arjuna, guggul for similar purposes — these can complement rather than replace each other.
Buying guide for India
When shopping on Amazon.in, prioritise products that clearly state:
- The standardised active compound percentage
- Third-party testing (NSF, USP, or Informed Sport)
- The form of ASU (extract vs whole herb vs isolate)
- Vegetarian capsule certification if that matters to you
Generic “natural” or “herbal” labels without standardisation information are a red flag. The price difference between a well-made and a poorly-made ASU supplement is often small — the difference in efficacy is not.
Bottom line
ASU has Key citations: PMID 31328413, PMID 14576991, PMID 21586377 for knee-pain. Used consistently at the right dose, it is a reasonable addition to a wellness protocol for those dealing with these concerns.
Supplements mentioned

ASU
Omega-3 · 300 mg/day · 30 caps
People also ask
What is the best time to take ASU in India?
Is ASU available in India and what brands should I look for?
Can vegetarians and vegans take ASU?
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