What it is
Reduced L-Glutathione (Setria) is a tripeptide antioxidant supplement that supports the body's natural detoxification processes. It is formulated to aid liver function and combat oxidative stress.
Supplement · Liver & Hepatoprotective
Reduced L-Glutathione (Setria)
500 mg · vegan · gluten-free · 60 caps
sluggish-detoxificationoxidative stressskin-breakouts liverkidneyskin
Affiliate link · we earn from qualifying purchases. No paid placements.
How it works
Reduced L-Glutathione (Setria) acts as a master antioxidant, directly neutralizing free radicals and supporting the liver's phase II detoxification enzymes. It also plays a role in regenerating other antioxidants like Vitamin C and E.
Who should take it
Adults looking to address sluggish detox, fatigue, skin breakouts. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
Avoid / careful
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
When to take it
Morning
Noon
Evening
Night
How to take it
With food
Empty stomach
Before food
FAQs
Frequently asked
How long does it take to see results?
Detoxification markers may show measurable improvements within 4-8 weeks of consistent daily use.
Can I combine it with other supplements?
Yes, it can be layered into a broader protocol. Consult a healthcare professional for personalized recommendations.
What is the difference between L-Glutathione and Reduced L-Glutathione?
Reduced L-Glutathione is the active, bioavailable form that the body readily uses for antioxidant and detoxification functions.
Research
6 studies · 2010–2024
Evidence grade
ABCD
B · B · emerging-to-moderate human evidence for liver detoxification and elimination
From the blog
Editorial notes
SacredBod's longer take on Reduced L-Glutathione (Setria) — context the structured blocks above don't capture.
About Reduced L-Glutathione (Setria)
Reduced L-Glutathione (Setria) is a liver & hepatoprotective supplement used to support liver detoxification and elimination. Master antioxidant tripeptide for liver and skin. It is available in capsule form and dosed for adults in India and internationally. As a western-tradition entry in the SacredBod catalog, it is positioned as a single-ingredient option that can be used on its own or layered into a broader protocol. Reduced L-Glutathione (Setria) works through the mechanisms characteristic of its class — see the mechanism and research sections for detail. It primarily acts on the liver, kidneys, lymphatic system, and effects are dose-dependent, typically becoming measurable within 4-8 weeks for detox markers. Consistency matters more than dose size for this category.
Evidence
Reduced L-Glutathione (Setria) carries an evidence grade of B in the SacredBod catalog, reflecting good-but-limited human evidence for liver detoxification and elimination. Master antioxidant tripeptide for liver and skin. Benefits are cumulative rather than immediate, typically becoming noticeable within 4-8 weeks for detox markers, and individual response varies.
Dosing
A typical dose is 500 mg, taken with food, usually in the morning. Start at the lower end, assess tolerance, and stay consistent; more is not automatically better.
Cautions
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
Who it’s for
Adults looking to address sluggish detox, fatigue, skin breakouts. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
As part of the Liver & Hepatoprotective category, Reduced L-Glutathione (Setria) can be used on its own or layered into a broader protocol — see the Goes with panel for evidence-aligned pairings.
Added to your stack.