What it is
Glycine (Sleep) is a single-ingredient supplement providing the amino acid glycine, used to improve sleep quality and promote relaxation. It is available in capsule form for adults.
Supplement · Mood, Anxiety & Emotional Balance
Glycine (Sleep)
500 mg · vegan · gluten-free · 90 caps
difficulty-falling-asleeprestless-sleepdaytime-fatigue brain
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How it works
Glycine acts as an inhibitory neurotransmitter in the central nervous system, particularly in the brainstem and hypothalamus. It binds to glycine receptors, which can lead to a decrease in core body temperature and promote sleep onset and maintenance.
Who should take it
Adults looking to address difficulty falling asleep, restless sleep, daytime fatigue. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
Avoid / careful
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
When to take it
Morning
Noon
Evening
Night
How to take it
With food
Empty stomach
Before food
FAQs
Frequently asked
How quickly can I expect to see results from Glycine (Sleep)?
Noticeable improvements in sleep quality and relaxation are typically observed within 1 to 3 weeks of consistent daily use.
Can Glycine (Sleep) be taken with other sleep aids?
While glycine can be layered into a protocol, consult your healthcare provider before combining it with other sleep medications or supplements to avoid potential interactions.
Are there any side effects of taking Glycine (Sleep)?
Side effects are uncommon at the recommended dose. Some individuals may experience mild gastrointestinal upset when first starting the supplement.
Research
6 studies · 2010–2024
Evidence grade
ABCD
C · C · emerging-to-moderate human evidence for sleep quality and relaxation
From the blog
Editorial notes
SacredBod's longer take on Glycine (Sleep) — context the structured blocks above don't capture.
About Glycine (Sleep)
Glycine (Sleep) is a mood, anxiety & emotional balance supplement used to support sleep quality and relaxation. Glycine for deep sleep and calm. It is available in capsule form and dosed for adults in India and internationally. As a western-tradition entry in the SacredBod catalog, it is positioned as a single-ingredient option that can be used on its own or layered into a broader protocol. Glycine (Sleep) works through the mechanisms characteristic of its class — see the mechanism and research sections for detail. It primarily acts on the brain, nervous system, and effects are dose-dependent, typically becoming measurable within 1-3 weeks for noticeable sleep and calm. Consistency matters more than dose size for this category.
Evidence
Glycine (Sleep) carries an evidence grade of C in the SacredBod catalog, reflecting emerging human evidence for sleep quality and relaxation. Glycine for deep sleep and calm. Benefits are cumulative rather than immediate, typically becoming noticeable within 1-3 weeks for noticeable sleep and calm, and individual response varies.
Dosing
A typical dose is 500 mg, taken with food, usually in the morning. Start at the lower end, assess tolerance, and stay consistent; more is not automatically better.
Cautions
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
Who it’s for
Adults looking to address difficulty falling asleep, restless sleep, daytime fatigue. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
As part of the Mood, Anxiety & Emotional Balance category, Glycine (Sleep) can be used on its own or layered into a broader protocol — see the Goes with panel for evidence-aligned pairings.
Added to your stack.