What it is
Sulforaphane (Glucoraphanin) is a compound derived from cruciferous vegetables, primarily broccoli sprouts. It is used to support the body's natural detoxification processes and antioxidant defence mechanisms.
Supplement · Liver & Hepatoprotective
Sulforaphane (Glucoraphanin)
30 mg · vegan · gluten-free · 60 caps
sluggish-detoxificationfatigueskin-breakouts liverkidneylymphatic system
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How it works
Sulforaphane activates the Nrf2 pathway, a key regulator of cellular defence against oxidative stress. This activation upregulates the production of phase II detoxification enzymes in the liver and enhances the body's antioxidant capacity.
Who should take it
Adults looking to address sluggish detox, fatigue, skin breakouts. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
Avoid / careful
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
When to take it
Morning
Noon
Evening
Night
How to take it
With food
Empty stomach
Before food
FAQs
Frequently asked
How long does it take to see results?
Detoxification markers may show measurable changes within 4-8 weeks of consistent daily use.
Can I take this with other supplements?
Yes, sulforaphane can be layered into a broader protocol. Consult a healthcare provider if you are on prescription medications.
What is the best way to take sulforaphane?
It is generally recommended to take sulforaphane capsules with food to optimize absorption and minimize potential gastrointestinal discomfort.
Research
6 studies · 2010–2024
Evidence grade
ABCD
B · B · emerging-to-moderate human evidence for liver detoxification and elimination
From the blog
Editorial notes
SacredBod's longer take on Sulforaphane (Glucoraphanin) — context the structured blocks above don't capture.
About Sulforaphane (Glucoraphanin)
Sulforaphane (Glucoraphanin) is a liver & hepatoprotective supplement used to support liver detoxification and elimination. Broccoli sulforaphane for Nrf2 detox and antioxidant defence. It is available in capsule form and dosed for adults in India and internationally. As a western-tradition entry in the SacredBod catalog, it is positioned as a single-ingredient option that can be used on its own or layered into a broader protocol. Sulforaphane (Glucoraphanin) works through the mechanisms characteristic of its class — see the mechanism and research sections for detail. It primarily acts on the liver, kidneys, lymphatic system, and effects are dose-dependent, typically becoming measurable within 4-8 weeks for detox markers. Consistency matters more than dose size for this category.
Evidence
Sulforaphane (Glucoraphanin) carries an evidence grade of B in the SacredBod catalog, reflecting good-but-limited human evidence for liver detoxification and elimination. Broccoli sulforaphane for Nrf2 detox and antioxidant defence. Benefits are cumulative rather than immediate, typically becoming noticeable within 4-8 weeks for detox markers, and individual response varies.
Dosing
A typical dose is 30 mg, taken with food, usually in the morning. Start at the lower end, assess tolerance, and stay consistent; more is not automatically better.
Cautions
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
Who it’s for
Adults looking to address sluggish detox, fatigue, skin breakouts. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
As part of the Liver & Hepatoprotective category, Sulforaphane (Glucoraphanin) can be used on its own or layered into a broader protocol — see the Goes with panel for evidence-aligned pairings.
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