What it is
Luteolin is a plant-derived flavonoid supplement used to support immune resilience and modulate inflammatory responses. It is recognized for its potential to influence mast cell activity and neuroinflammation.
Supplement · Immune Advanced Protocols
Luteolin
500 mg · vegan · gluten-free · 90 caps
frequent-respiratory-infectionsslow-recoveryseasonal-allergies immune systembrain
Affiliate link · we earn from qualifying purchases. No paid placements.
How it works
Luteolin inhibits key inflammatory pathways, including the release of histamine from mast cells and the production of pro-inflammatory cytokines like IL-6. It also exhibits antioxidant properties, protecting cells from oxidative stress.
Who should take it
Adults looking to address frequent infections, low immunity, slow recovery. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
Avoid / careful
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
When to take it
Morning
Noon
Evening
Night
How to take it
With food
Empty stomach
Before food
FAQs
Frequently asked
Can Luteolin help with seasonal allergies?
Yes, Luteolin's ability to stabilize mast cells and reduce histamine release may offer relief from symptoms associated with seasonal allergies.
How long does it take to see results from Luteolin?
For immune resilience and inflammatory modulation, effects are typically noticeable within 2-6 weeks of consistent daily use.
Is Luteolin safe for long-term use?
At recommended doses, Luteolin is generally well-tolerated. However, consult with a healthcare professional for personalized long-term usage guidance.
Research
6 studies · 2010–2024
Evidence grade
ABCD
C · C · emerging-to-moderate human evidence for immune resilience
From the blog
Editorial notes
SacredBod's longer take on Luteolin — context the structured blocks above don't capture.
About Luteolin
Luteolin is a immune advanced protocols supplement used to support immune resilience. Flavone for mast-cell and brain inflammation. It is available in capsule form and dosed for adults in India and internationally. As a western-tradition entry in the SacredBod catalog, it is positioned as a single-ingredient option that can be used on its own or layered into a broader protocol. Luteolin works through the mechanisms characteristic of its class — see the mechanism and research sections for detail. It primarily acts on the immune system, lymphatic system, and effects are dose-dependent, typically becoming measurable within 2-6 weeks for immune resilience. Consistency matters more than dose size for this category.
Evidence
Luteolin carries an evidence grade of C in the SacredBod catalog, reflecting emerging human evidence for immune resilience. Flavone for mast-cell and brain inflammation. Benefits are cumulative rather than immediate, typically becoming noticeable within 2-6 weeks for immune resilience, and individual response varies.
Dosing
A typical dose is 500 mg, taken with food, usually in the morning. Start at the lower end, assess tolerance, and stay consistent; more is not automatically better.
Cautions
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
Who it’s for
Adults looking to address frequent infections, low immunity, slow recovery. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
As part of the Immune Advanced Protocols category, Luteolin can be used on its own or layered into a broader protocol — see the Goes with panel for evidence-aligned pairings.
Added to your stack.