What it is
Makoy (Black Nightshade) is an ayurvedic supplement used to support liver detoxification and elimination. It is available in capsule form and is suitable for adults seeking targeted liver support.
Supplement · Liver & Hepatoprotective
Makoy (Black Nightshade)
500 mg · vegan · gluten-free · 90 caps
sluggish-detoxificationfatigueskin-breakouts liverkidneylymphatic system
Affiliate link · we earn from qualifying purchases. No paid placements.
How it works
Makoy primarily acts on the liver and kidneys to enhance detoxification pathways. Its effects on detox markers typically become measurable within 4-8 weeks of consistent use.
Who should take it
Adults looking to address sluggish detox, fatigue, skin breakouts. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
Avoid / careful
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
When to take it
Morning
Noon
Evening
Night
How to take it
With food
Empty stomach
Before food
FAQs
Frequently asked
How long does it take to see results from Makoy?
Detox markers typically show measurable changes within 4-8 weeks of consistent daily dosing.
Can Makoy be combined with other supplements?
Yes, Makoy can be layered into a broader protocol. However, consult a healthcare professional if you are on prescription medications.
What is the recommended dosage for Makoy?
The standard adult dose is 500 mg per day.
Research
6 studies · 2010–2024
Evidence grade
ABCD
C · C · emerging-to-moderate human evidence for liver detoxification and elimination
From the blog
Editorial notes
SacredBod's longer take on Makoy (Black Nightshade) — context the structured blocks above don't capture.
About Makoy (Black Nightshade)
Makoy (Black Nightshade) is a liver & hepatoprotective supplement used to support liver detoxification and elimination. Makoy for liver, dropsy and inflammation. It is available in capsule form and dosed for adults in India and internationally. As a ayurveda-tradition entry in the SacredBod catalog, it is positioned as a single-ingredient option that can be used on its own or layered into a broader protocol. Makoy (Black Nightshade) works through the mechanisms characteristic of its class — see the mechanism and research sections for detail. It primarily acts on the liver, kidneys, lymphatic system, and effects are dose-dependent, typically becoming measurable within 4-8 weeks for detox markers. Consistency matters more than dose size for this category.
Evidence
Makoy (Black Nightshade) carries an evidence grade of C in the SacredBod catalog, reflecting emerging human evidence for liver detoxification and elimination. Makoy for liver, dropsy and inflammation. Benefits are cumulative rather than immediate, typically becoming noticeable within 4-8 weeks for detox markers, and individual response varies.
Dosing
A typical dose is 500 mg, taken with food, usually in the morning. Start at the lower end, assess tolerance, and stay consistent; more is not automatically better.
Cautions
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
Who it’s for
Adults looking to address sluggish detox, fatigue, skin breakouts. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
As part of the Liver & Hepatoprotective category, Makoy (Black Nightshade) can be used on its own or layered into a broader protocol — see the Goes with panel for evidence-aligned pairings.
Added to your stack.