What it is
PT-141 (Bremelanotide) is a synthetic peptide analog of alpha-melanocyte-stimulating hormone. It is researched for its potential to enhance sexual desire and arousal by activating melanocortin receptors in the brain.
Supplement · Peptide
PT-141 (Bremelanotide)
10 mg · vegan · gluten-free · 30 caps
low-libidoerectile-dysfunction brainpituitary glandadrenal gland
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How it works
PT-141 activates melanocortin receptors (primarily MC3R and MC4R) in the central nervous system, which are involved in regulating sexual function and desire. This activation is thought to influence dopaminergic pathways and other neurotransmitters crucial for arousal.
Who should take it
Adults looking to address hormonal imbalance, low libido, irregular cycles. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
Avoid / careful
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
When to take it
Morning
Noon
Evening
Night
How to take it
With food
Empty stomach
Before food
FAQs
Frequently asked
How quickly does PT-141 work?
Effects on sexual desire and arousal can be experienced within hours to a day after administration, though consistent use may be required for sustained benefits.
Can PT-141 be used by both men and women?
Yes, PT-141 has been studied and is used for both male and female sexual dysfunction, targeting libido and arousal.
What are the common side effects?
The most frequently reported side effect is transient nausea. Flushing and headache are also possible but less common.
Research
6 studies · 2010–2024
Evidence grade
ABCD
C · C · emerging-to-moderate human evidence for hormonal balance
From the blog
Editorial notes
SacredBod's longer take on PT-141 (Bremelanotide) — context the structured blocks above don't capture.
About PT-141 (Bremelanotide)
PT-141 (Bremelanotide) is a peptide supplement used to support hormonal balance. Melanocortin peptide researched for libido. It is available in capsule form and dosed for adults in India and internationally. As a peptide-tradition entry in the SacredBod catalog, it is positioned as a single-ingredient option that can be used on its own or layered into a broader protocol. PT-141 (Bremelanotide) works through the mechanisms characteristic of its class — see the mechanism and research sections for detail. It primarily acts on the endocrine system, thyroid, reproductive system, and effects are dose-dependent, typically becoming measurable within 4-12 weeks for hormonal shifts. Consistency matters more than dose size for this category.
Evidence
PT-141 (Bremelanotide) carries an evidence grade of C in the SacredBod catalog, reflecting emerging human evidence for hormonal balance. Melanocortin peptide researched for libido. Benefits are cumulative rather than immediate, typically becoming noticeable within 4-12 weeks for hormonal shifts, and individual response varies.
Dosing
A typical dose is 10 mg, taken with food, usually in the morning. Start at the lower end, assess tolerance, and stay consistent; more is not automatically better.
Cautions
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
Who it’s for
Adults looking to address hormonal imbalance, low libido, irregular cycles. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
As part of the Peptide category, PT-141 (Bremelanotide) can be used on its own or layered into a broader protocol — see the Goes with panel for evidence-aligned pairings.
Added to your stack.