What it is
Shiitake mushroom extract, standardized for lentinan, a beta-glucan polysaccharide. It is used to enhance immune system function and resilience.
Supplement · Mushroom
Shiitake (Lentinan)
500 mg · vegan · gluten-free · 90 caps
frequent infectionsslow-recoverylow-immunity immune systemlymphatic systemgut
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How it works
Lentinan, a key beta-glucan in shiitake, activates immune cells like macrophages and T-cells. It also influences cytokine production to modulate immune responses, contributing to improved immune surveillance.
Who should take it
Adults looking to address frequent infections, low immunity, slow recovery. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
Avoid / careful
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
When to take it
Morning
Noon
Evening
Night
How to take it
With food
Empty stomach
Before food
FAQs
Frequently asked
How long does it take to see results?
Immune support effects are typically noticeable within 2 to 6 weeks of consistent daily use.
Can I take Shiitake with other supplements?
Yes, it can be layered with other supplements. Consult a healthcare provider if you are on prescription medications.
What is Lentinan?
Lentinan is a specific type of beta-glucan polysaccharide found in shiitake mushrooms, known for its immune-modulating properties.
Research
6 studies · 2010–2024
Evidence grade
ABCD
B · B · emerging-to-moderate human evidence for immune resilience
From the blog
Editorial notes
SacredBod's longer take on Shiitake (Lentinan) — context the structured blocks above don't capture.
About Shiitake (Lentinan)
Shiitake (Lentinan) is a mushroom supplement used to support immune resilience. Lentinan-rich culinary mushroom for immune and lipid support. It is available in capsule form and dosed for adults in India and internationally. As a mushroom-tradition entry in the SacredBod catalog, it is positioned as a single-ingredient option that can be used on its own or layered into a broader protocol.
How it works
Shiitake (Lentinan) works through the mechanisms characteristic of its class — see the mechanism and research sections for detail. It primarily acts on the immune system, lymphatic system, and effects are dose-dependent, typically becoming measurable within 2-6 weeks for immune resilience. Consistency matters more than dose size for this category.
Who it’s for
Adults looking to address frequent infections, low immunity, slow recovery. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
Evidence
Shiitake (Lentinan) carries an evidence grade of B in the SacredBod catalog. Lentinan-rich culinary mushroom for immune and lipid support. See the Research panel above for the underlying studies, participant counts and typical effect sizes.
Dosing & timing
Typical label dose is 500 mg in capsule form. Most adults can expect noticeable effects within 2-6 weeks for immune resilience. Consistency matters more than a single large dose — take it daily and re-evaluate against your blood markers at 8–12 weeks.
Cautions
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
As part of the Mushroom category, Shiitake (Lentinan) can be used on its own or layered into a broader protocol — see the Goes with panel for synergistic pairings.
Added to your stack.