What it is
Sodium butyrate is the sodium salt of butyric acid in an enteric-coated capsule, delivering free butyrate to the lower GI for direct colonocyte uptake.
Supplement · Gut Health & SCFA
Sodium Butyrate (Enteric Coated)
500–1500 mg · vegan · gluten-free · 60 caps
inflammationirregular-bowel-movements gut
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How it works
Same biology as tributyrin — colonocyte fuel and HDAC modulation — with faster release once the enteric coating dissolves in the small intestine.
Who should take it
Adults wanting immediate colonic butyrate without triglyceride hydrolysis delay.
Avoid / careful
Watch sodium load at high daily doses. Active IBD requires medical oversight.
When to take it
Morning
Noon
Evening
Night
How to take it
With food
Empty stomach
Before food
FAQs
Frequently asked
What is the difference between sodium butyrate and tributyrin?
Sodium butyrate is the direct salt form, while tributyrin is a triglyceride that must be hydrolyzed in the gut to release butyrate. Sodium butyrate offers faster, direct absorption in the colon.
Can sodium butyrate help with IBS symptoms?
Sodium butyrate can help improve gut barrier function and reduce inflammation, which may alleviate symptoms like diarrhea, constipation, and bloating associated with IBS.
Is the enteric coating important?
Yes, the enteric coating is crucial. It prevents the premature breakdown of sodium butyrate by stomach acid, ensuring it reaches the colon where it can be effectively utilized by colonocytes.
Research summary
A plain-English read of the literature behind this supplement. Not a clinical recommendation.
Polish IBS RCTs (Banasiewicz) show symptom improvements at 300 mg/day over 12 weeks.
From the blog
Editorial notes
SacredBod's longer take on Sodium Butyrate (Enteric Coated) — context the structured blocks above don't capture.
Sodium Butyrate (Enteric Coated) is a gut health & scfa supplement. Sodium butyrate is the sodium salt of butyric acid in an enteric-coated capsule, delivering free butyrate to the lower GI for direct colonocyte uptake.
How it works
Same biology as tributyrin — colonocyte fuel and HDAC modulation — with faster release once the enteric coating dissolves in the small intestine.
Who it’s for
Adults wanting immediate colonic butyrate without triglyceride hydrolysis delay.
Dosage & timing
- Typical dose: 500–1500 mg
- Best time: morning
- With food: with-food
- Expected onset: 4–8 weeks for gut barrier markers.
India context
Availability on Amazon India is currently limited or import-only for this form. International brands (iHerb, NOW Foods, Doctor’s Best) ship to India with variable customs handling. Local Ayurvedic equivalents may offer overlapping benefits.
Safety
Watch sodium load at high daily doses. Active IBD requires medical oversight.
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