What it is
TB-500 is a synthetic peptide fragment of Thymosin Beta-4, researched for its role in tissue repair and regeneration. It is formulated as a supplement to target musculoskeletal and joint health.
Supplement · Peptide
TB-500 (Thymosin Beta-4)
10 mg · vegan · gluten-free · 30 caps
joint stiffnessmuscle-weaknessjoint pain jointmusclebone
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How it works
TB-500 facilitates cell migration, differentiation, and proliferation, promoting the repair of damaged tissues in muscles, tendons, ligaments, and joints. Its effects on joint comfort are typically observed within 4-12 weeks of consistent use.
Who should take it
Adults looking to address joint stiffness, muscle weakness, joint pain. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
Avoid / careful
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
When to take it
Morning
Noon
Evening
Night
How to take it
With food
Empty stomach
Before food
FAQs
Frequently asked
How long does it take to see results with TB-500?
Benefits for joint comfort and tissue repair are typically observed within 4 to 12 weeks of consistent daily dosing.
Can TB-500 be combined with other supplements?
TB-500 can be layered into a broader protocol. However, consult a healthcare professional if you are on prescription medication affecting similar pathways.
What are the common side effects of TB-500?
Side effects are uncommon at recommended doses. Mild gastrointestinal upset may occur when first starting the supplement.
Research
6 studies · 2010–2024
Evidence grade
ABCD
C · C · emerging-to-moderate human evidence for joint and musculoskeletal health
From the blog
Editorial notes
SacredBod's longer take on TB-500 (Thymosin Beta-4) — context the structured blocks above don't capture.
About TB-500 (Thymosin Beta-4)
TB-500 (Thymosin Beta-4) is a peptide supplement used to support joint and musculoskeletal health. Thymosin fragment researched for recovery. It is available in capsule form and dosed for adults in India and internationally. As a peptide-tradition entry in the SacredBod catalog, it is positioned as a single-ingredient option that can be used on its own or layered into a broader protocol. TB-500 (Thymosin Beta-4) works through the mechanisms characteristic of its class — see the mechanism and research sections for detail. It primarily acts on the joints, muscles, bones, and effects are dose-dependent, typically becoming measurable within 4-12 weeks for joint comfort. Consistency matters more than dose size for this category.
Evidence
TB-500 (Thymosin Beta-4) carries an evidence grade of C in the SacredBod catalog, reflecting emerging human evidence for joint and musculoskeletal health. Thymosin fragment researched for recovery. Benefits are cumulative rather than immediate, typically becoming noticeable within 4-12 weeks for joint comfort, and individual response varies.
Dosing
A typical dose is 10 mg, taken with food, usually in the morning. Start at the lower end, assess tolerance, and stay consistent; more is not automatically better.
Cautions
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
Who it’s for
Adults looking to address joint stiffness, muscle weakness, joint pain. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
As part of the Peptide category, TB-500 (Thymosin Beta-4) can be used on its own or layered into a broader protocol — see the Goes with panel for evidence-aligned pairings.
Added to your stack.