What it is
Zi Su Ye, or Perilla Leaf, is a single-ingredient TCM supplement. It is formulated to address symptoms associated with wind-cold invasion and digestive discomfort, particularly nausea and intolerance to seafood.
Supplement · Immune Advanced Protocols
Zi Su Ye (Perilla Leaf)
500 mg · vegan · gluten-free · 90 caps
common-coldnauseafood-intolerance lungsstomachlymphatic system
Affiliate link · we earn from qualifying purchases. No paid placements.
How it works
Perilla leaf contains compounds that modulate immune responses and calm the stomach. Its action on the respiratory system helps expel wind-cold pathogens, while its antiemetic properties reduce nausea and vomiting.
Who should take it
Adults looking to address frequent infections, low immunity, slow recovery. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
Avoid / careful
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
When to take it
Morning
Noon
Evening
Night
How to take it
With food
Empty stomach
Before food
FAQs
Frequently asked
What is 'wind-cold invasion' in TCM?
In TCM, wind-cold invasion refers to the onset of symptoms like chills, body aches, and nasal congestion, often associated with exposure to cold environments or pathogens.
Can Zi Su Ye help with motion sickness?
While primarily indicated for nausea related to wind-cold and seafood, its antiemetic properties may offer some benefit for other forms of nausea, though specific clinical data for motion sickness is limited.
How long does it take to see effects?
For immune resilience, effects are typically measurable within 2-6 weeks of consistent daily use. Digestive benefits may be experienced sooner.
Research
6 studies · 2010–2024
Evidence grade
ABCD
C · C · emerging-to-moderate human evidence for immune resilience
From the blog
Editorial notes
SacredBod's longer take on Zi Su Ye (Perilla Leaf) — context the structured blocks above don't capture.
About Zi Su Ye (Perilla Leaf)
Zi Su Ye (Perilla Leaf) is a immune advanced protocols supplement used to support immune resilience. Perilla leaf for wind-cold, nausea and seafood. It is available in capsule form and dosed for adults in India and internationally. As a tcm-tradition entry in the SacredBod catalog, it is positioned as a single-ingredient option that can be used on its own or layered into a broader protocol. Zi Su Ye (Perilla Leaf) works through the mechanisms characteristic of its class — see the mechanism and research sections for detail. It primarily acts on the immune system, lymphatic system, and effects are dose-dependent, typically becoming measurable within 2-6 weeks for immune resilience. Consistency matters more than dose size for this category.
Evidence
Zi Su Ye (Perilla Leaf) carries an evidence grade of C in the SacredBod catalog, reflecting emerging human evidence for immune resilience. Perilla leaf for wind-cold, nausea and seafood. Benefits are cumulative rather than immediate, typically becoming noticeable within 2-6 weeks for immune resilience, and individual response varies.
Dosing
A typical dose is 500 mg, taken with food, usually in the morning. Start at the lower end, assess tolerance, and stay consistent; more is not automatically better.
Cautions
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
Who it’s for
Adults looking to address frequent infections, low immunity, slow recovery. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
As part of the Immune Advanced Protocols category, Zi Su Ye (Perilla Leaf) can be used on its own or layered into a broader protocol — see the Goes with panel for evidence-aligned pairings.
Added to your stack.