What it is
Bacillus subtilis DE111 is a spore-forming probiotic strain formulated to support digestive comfort and gut barrier integrity. It is available in capsule form and is suitable for adults seeking targeted digestive support.
Supplement · Probiotic
Bacillus subtilis DE111
5 billion CFU · vegan · gluten-free · 30 caps
bloatingindigestionirregular-bowel-movements gutstomach
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How it works
As a spore probiotic, Bacillus subtilis DE111 survives stomach acid and germinates in the intestines, where it exerts its beneficial effects. It works by modulating the gut microbiota and supporting the intestinal lining.
Who should take it
Adults looking to address bloating, indigestion, irregular bowel movements. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
Avoid / careful
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
When to take it
Morning
Noon
Evening
Night
How to take it
With food
Empty stomach
Before food
FAQs
Frequently asked
How long does it take to see results?
Digestive comfort improvements are typically observed within 1-4 weeks of consistent daily use.
Can I take this with other supplements?
Yes, Bacillus subtilis DE111 can be layered into a broader supplement protocol. Consult a healthcare professional if you have specific concerns.
What makes spore probiotics different?
Spore probiotics are naturally protected by a hard shell, allowing them to survive the harsh acidic environment of the stomach and reach the intestines intact.
Research
6 studies · 2010–2024
Evidence grade
ABCD
C · C · emerging-to-moderate human evidence for digestive comfort and gut-barrier integrity
From the blog
Editorial notes
SacredBod's longer take on Bacillus subtilis DE111 — context the structured blocks above don't capture.
About Bacillus subtilis DE111
Bacillus subtilis DE111 is a probiotic supplement used to support digestive comfort and gut-barrier integrity. Spore probiotic for digestion and immunity. It is available in capsule form and dosed for adults in India and internationally. As a western-tradition entry in the SacredBod catalog, it is positioned as a single-ingredient option that can be used on its own or layered into a broader protocol. Bacillus subtilis DE111 works through the mechanisms characteristic of its class — see the mechanism and research sections for detail. It primarily acts on the gut, intestines, stomach, and effects are dose-dependent, typically becoming measurable within 1-4 weeks for digestive comfort. Consistency matters more than dose size for this category.
Evidence
Bacillus subtilis DE111 carries an evidence grade of C in the SacredBod catalog, reflecting emerging human evidence for digestive comfort and gut-barrier integrity. Spore probiotic for digestion and immunity. Benefits are cumulative rather than immediate, typically becoming noticeable within 1-4 weeks for digestive comfort, and individual response varies.
Dosing
A typical dose is 5 billion CFU, taken with food, usually in the morning. Start at the lower end, assess tolerance, and stay consistent; more is not automatically better.
Cautions
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
Who it’s for
Adults looking to address bloating, indigestion, irregular bowel movements. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
As part of the Probiotic category, Bacillus subtilis DE111 can be used on its own or layered into a broader protocol — see the Goes with panel for evidence-aligned pairings.
Added to your stack.