What it is
DGL is licorice root with glycyrrhizin removed — preserving the mucosal benefits of flavonoids while eliminating the BP-raising side effect of glycyrrhizin.
Supplement · Gut Health & Mucosal
DGL Licorice (Deglycyrrhizinated)
Deglycyrrhizinated licorice
380–760 mg chewed before meals · vegan · gluten-free · 60 caps
indigestionpeptic-ulcer stomachgut
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How it works
DGL stimulates mucin production and supports prostaglandin-mediated mucosal defense in the stomach. Chewable form ensures direct contact with esophageal and gastric mucosa.
Who should take it
Adults with chronic gastritis, peptic ulcer recovery, GERD, or those tapering off long-term PPI therapy.
Avoid / careful
Generally well-tolerated unlike regular licorice. Chew the tablet — swallowing whole reduces effect.
When to take it
Morning
Noon
Evening
Night
How to take it
With food
Empty stomach
Before food
FAQs
Frequently asked
Can I swallow DGL tablets whole?
No, for optimal results, DGL tablets should be chewed thoroughly. Swallowing them whole reduces their direct contact with the esophageal and gastric mucosa, diminishing their effectiveness.
Is DGL safe for long-term use?
DGL is generally considered safe for long-term use as the glycyrrhizin, which causes side effects like increased blood pressure, has been removed. However, always consult with a healthcare professional for personalized advice.
How does DGL differ from regular licorice?
The key difference is the removal of glycyrrhizin from DGL. Regular licorice contains glycyrrhizin, which can lead to side effects such as elevated blood pressure and potassium depletion, while DGL retains the mucosal-protective benefits without these risks.
Research summary
A plain-English read of the literature behind this supplement. Not a clinical recommendation.
Older trials show comparable ulcer healing to cimetidine. Modern use is widespread for GERD adjunct.
From the blog
Editorial notes
SacredBod's longer take on DGL Licorice (Deglycyrrhizinated) — context the structured blocks above don't capture.
DGL Licorice (Deglycyrrhizinated) is a gut health & mucosal supplement. DGL is licorice root with glycyrrhizin removed — preserving the mucosal benefits of flavonoids while eliminating the BP-raising side effect of glycyrrhizin.
How it works
DGL stimulates mucin production and supports prostaglandin-mediated mucosal defense in the stomach. Chewable form ensures direct contact with esophageal and gastric mucosa.
Who it’s for
Adults with chronic gastritis, peptic ulcer recovery, GERD, or those tapering off long-term PPI therapy.
Dosage & timing
- Typical dose: 380–760 mg chewed before meals
- Best time: morning
- With food: before-food
- Expected onset: 2–6 weeks for gastritis and ulcer symptoms.
India context
Availability on Amazon India is currently limited or import-only for this form. International brands (iHerb, NOW Foods, Doctor’s Best) ship to India with variable customs handling. Local Ayurvedic equivalents may offer overlapping benefits.
Safety
Generally well-tolerated unlike regular licorice. Chew the tablet — swallowing whole reduces effect.
Added to your stack.