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NSI-189 (Neurogenesis) — SacredBod supplement bottle (illustrative)
Supplement · Nootropic & Mood

NSI-189 (Neurogenesis)

As directed · vegan · gluten-free · 60 caps

low-moodmemory-loss brain
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Overview Stacks Timing Related FAQs

What it is

NSI-189 (Neurogenesis) is a nootropic & mood supplement. NSI-189 is an investigational nicotinamide-derived compound studied in clinical trials for depression via hippocampal neurogenesis. Used in adult dosing protocols in India and internationally, it is sold as a single-ingredient supplement.

How it works

It is reported to stimulate proliferation of hippocampal neural progenitors and increase hippocampal volume, with antidepressant and pro-cognitive effects studied in trials. Effects are dose-dependent and typically measurable within weeks.

Who should take it

Adults exploring neurogenesis support for mood and cognition; clinical evidence is mixed/early.

Avoid / careful

Investigational, not an approved drug; long-term safety unestablished. Not a substitute for treatment of depression — consult a clinician.

When to take it

Morning
Noon
Evening
Night

How to take it

With food
Empty stomach
Before food

Flexible — works in any of the above.

FAQs

Frequently asked

Is NSI-189 approved by regulatory bodies?
No, NSI-189 is an investigational compound and is not approved by major regulatory bodies for any medical condition.
What is the primary proposed mechanism of NSI-189?
The primary proposed mechanism is the stimulation of hippocampal neurogenesis, potentially increasing hippocampal volume and improving mood and cognitive function.
Can NSI-189 be used to treat clinical depression?
While studied for depression, NSI-189 is not a substitute for established medical treatments. Always consult a qualified clinician for diagnosis and treatment of depression.

Editorial notes

SacredBod's longer take on NSI-189 (Neurogenesis) — context the structured blocks above don't capture.

About NSI-189 (Neurogenesis)

Investigational compound studied for hippocampal neurogenesis and mood..

How it works

It is reported to stimulate proliferation of hippocampal neural progenitors and increase hippocampal volume, with antidepressant and pro-cognitive effects studied in trials. Effects are dose-dependent and typically measurable within weeks.

Who it’s for

Adults exploring neurogenesis support for mood and cognition; clinical evidence is mixed/early.

Dosage & timing

  • Typical dose: As directed
  • Best time: morning
  • With food: flexible
  • Expected onset: Weeks.

Safety

Investigational, not an approved drug; long-term safety unestablished. Not a substitute for treatment of depression — consult a clinician.

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