What it is
Phosphatidylserine (PS) is a phospholipid crucial for cell membrane structure and function, particularly in the brain. This 100mg formulation is designed to support cognitive functions and stress response.
Supplement · Nootropic & Choline
Phosphatidylserine (100mg)
500 mg · vegan · gluten-free · 90 caps
brain-fogmemory-lossattention-difficulty brainadrenal gland
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How it works
PS integrates into neuronal cell membranes, facilitating neurotransmitter release and signal transduction. It helps regulate the hypothalamic-pituitary-adrenal (HPA) axis, reducing cortisol secretion in response to stress.
Who should take it
Adults looking to address brain fog, memory decline, attention difficulty. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
Avoid / careful
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
When to take it
Morning
Noon
Evening
Night
How to take it
With food
Empty stomach
Before food
FAQs
Frequently asked
How long does it take to see effects from Phosphatidylserine?
Noticeable cognitive effects are typically observed within 2-8 weeks of consistent daily use.
Can Phosphatidylserine help with stress?
Yes, Phosphatidylserine helps regulate the HPA axis and can reduce elevated cortisol levels associated with stress.
Is Phosphatidylserine safe for long-term use?
At recommended doses, Phosphatidylserine is generally considered safe for long-term use by adults. However, consult a healthcare provider for personalized advice.
Research
6 studies · 2010–2024
Evidence grade
ABCD
C · C · emerging-to-moderate human evidence for brain fog and memory concerns
From the blog
Editorial notes
SacredBod's longer take on Phosphatidylserine (100mg) — context the structured blocks above don't capture.
About Phosphatidylserine (100mg)
Phosphatidylserine (100mg) is a nootropic & choline supplement used to support brain fog and memory concerns. PS for memory, focus and cortisol balance. It is available in capsule form and dosed for adults in India and internationally. As a western-tradition entry in the SacredBod catalog, it is positioned as a single-ingredient option that can be used on its own or layered into a broader protocol. Phosphatidylserine (100mg) works through the mechanisms characteristic of its class — see the mechanism and research sections for detail. It primarily acts on the brain, nervous system, and effects are dose-dependent, typically becoming measurable within 2-8 weeks for noticeable cognitive effects. Consistency matters more than dose size for this category.
Evidence
Phosphatidylserine (100mg) carries an evidence grade of C in the SacredBod catalog, reflecting emerging human evidence for brain fog and memory concerns. PS for memory, focus and cortisol balance. Benefits are cumulative rather than immediate, typically becoming noticeable within 2-8 weeks for noticeable cognitive effects, and individual response varies.
Dosing
A typical dose is 500 mg, taken with food, usually in the morning. Start at the lower end, assess tolerance, and stay consistent; more is not automatically better.
Cautions
Pregnant or nursing women without clinician oversight. People on prescription medication affecting the same pathway should consult a doctor before combining. Side effects are uncommon at recommended doses but mild GI upset can occur when starting.
Who it’s for
Adults looking to address brain fog, memory decline, attention difficulty. Particularly relevant for people who prefer a targeted single ingredient and who have ruled out an underlying condition that needs medical care first.
As part of the Nootropic & Choline category, Phosphatidylserine (100mg) can be used on its own or layered into a broader protocol — see the Goes with panel for evidence-aligned pairings.
Added to your stack.