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Fatty Liver Support supplement stack (illustrative)
Stack · Liver & Hepatoprotective

Fatty Liver Support

Support for metabolic-associated fatty liver disease (MAFLD).

Abdominal discomfortFatigueElevated liver enzymesInsulin resistanceWeight gain
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Quick facts
  • 10 supplements
  • Evidence: B
  • 1/5/10 tier picker

Pick your depth

Same stack, three commitment levels.

FULL
10 supplements · max coverage
Berberine PhytosomeAlpha-Lipoic Acid High (600 mg)Myo-D-Chiro Inositol 40:1Choline Methyl Donor LiverCocoa FlavanolsChromium GTF NicotinateAkkermansia PasteurisedBanaba Leaf (Corosolic Acid)Benfotiamine (Fat-Soluble B1)Black Seed Oil (High Thymoquinone)
BUY Berberine Phytosome → BUY Alpha-Lipoic Acid High (600 mg) → BUY Myo-D-Chiro Inositol 40:1 → BUY Choline Methyl Donor Liver → BUY Cocoa Flavanols → BUY Chromium GTF Nicotinate → BUY Akkermansia Pasteurised → BUY Banaba Leaf (Corosolic Acid) → BUY Benfotiamine (Fat-Soluble B1) → BUY Black Seed Oil (High Thymoquinone) →
Overview Symptoms & markers

A targeted approach to support liver health in individuals with metabolic dysfunction-associated fatty liver disease. This stack focuses on improving insulin sensitivity, reducing inflammation, and supporting liver detoxification pathways.

What it's for

This stack is designed to address the underlying metabolic drivers of fatty liver disease. It aims to improve liver fat metabolism, reduce oxidative stress, and enhance the liver's natural detoxification processes.

Not for:This is not a substitute for medical treatment for severe liver disease or cirrhosis. Consult your doctor before starting any new supplement regimen.

Symptoms it can address

✓ Abdominal discomfort✓ Fatigue✓ Elevated liver enzymes✓ Insulin resistance✓ Weight gain
Evidence grade
ABCD

B · Pooled evidence for the stack as a whole. Individual supplements may have stronger or weaker grades — see their pages.

Members of the FULL stack

  1. Berberine Phytosome

    AMPK Activator & Glucose/Lipid Control · 550 mg

    Improves insulin sensitivity and activates AMPK, crucial for regulating liver fat metabolism and reducing inflammation.

    Details BUY →

  2. Alpha-Lipoic Acid High (600 mg)

    Antioxidant & Metabolic · 600 mg

    Potent antioxidant that combats oxidative stress and improves insulin sensitivity, supporting liver health.

    Details BUY →

  3. Myo-D-Chiro Inositol 40:1

    PCOS & Insulin Resistance · 2 g myo + 50 mg D-chiro

    Addresses insulin resistance and metabolic dysfunction, key drivers of fatty liver disease, by improving glucose uptake.

    Details BUY →

  4. Choline Methyl Donor Liver

    Liver & Hepatoprotective · 650 mg

    Essential for liver fat export and detoxification, preventing fat accumulation and supporting overall liver function.

    Details BUY →

  5. Cocoa Flavanols

    Botanical · 450 mg

    Enhances nitric oxide production, improving blood flow and metabolic flexibility, which aids in liver fat reduction.

    Details BUY →

  6. Chromium GTF Nicotinate

    Insulin Sensitivity · 200 mcg

    Supports insulin action and glucose metabolism, helping to regulate blood sugar levels and reduce hepatic fat deposition.

    Details BUY →

  7. Akkermansia Pasteurised

    Gut-Brain Axis · 10 billion cells

    Promotes a healthy gut microbiome, which is linked to reduced inflammation and improved metabolic health, indirectly benefiting the liver.

    Details BUY →

  8. Banaba Leaf (Corosolic Acid)

    Glycemic & Pancreatic · 32–48 mg of 1% corosolic acid

    Helps regulate blood sugar levels by mimicking insulin action, reducing the metabolic burden on the liver.

    Details BUY →

  9. Benfotiamine (Fat-Soluble B1)

    Vitamin · 300 mg

    Protects against advanced glycation end products (AGEs) and oxidative stress, supporting liver cell function.

    Details BUY →

  10. Black Seed Oil (High Thymoquinone)

    Lipid & Immune · 1000 mg

    Provides anti-inflammatory and antioxidant benefits, helping to mitigate liver damage and improve metabolic markers.

    Details BUY →

Ready to build your stack?

4–8 weeks to feel the full benefit. Start with MES if you're new — that's where most people land.

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