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Telomere Support Complex supplement stack (illustrative)
Stack · Longevity & NAD+

Telomere Support Complex

Supporting cellular aging and telomere length.

Cellular agingLongevity concernsAge-related decline
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Quick facts
  • 10 supplements
  • Evidence: C
  • 1/5/10 tier picker

Nutrients and compounds believed to support telomere maintenance, a marker of cellular aging.

What it's for

This stack includes ingredients like Astragalus, Resveratrol, and specific vitamins that research suggests may play a role in supporting telomere length and cellular health.

Not for:The direct impact of these supplements on human telomere length is still under research. Not a substitute for a healthy lifestyle.

Symptoms it can address

✓ Cellular aging✓ Longevity concerns✓ Age-related decline
Evidence grade
ABCD

C · Pooled evidence for the stack as a whole. Individual supplements may have stronger or weaker grades — see their pages.

Members of the FULL stack

  1. Astragalus Membranaceus (High Potency)

    Immune & Adaptogen · 1000 mg

    Supports telomere length and cellular health through its polysaccharides, a key component of the telomere support complex.

  2. Trans-Resveratrol High Dose (1 g)

    Longevity & Cardiovascular · 1000 mg

    Activates sirtuins, which are involved in DNA repair and cellular aging processes, potentially influencing telomere maintenance.

  3. Astragalus Polysaccharide APS

    Immune Advanced Protocols · 500 mg–2 g

    Provides concentrated astragalus polysaccharides, directly contributing to the stack's goal of supporting cellular aging and telomere length.

  4. Ergothioneine (Mushroom-Derived)

    Antioxidant & Longevity · varies

    Acts as a potent antioxidant, protecting cells from oxidative stress that can damage DNA and contribute to telomere shortening.

  5. Pterostilbene

    Longevity & NAD+ · 100 mg

    A potent antioxidant and sirtuin activator, complementing resveratrol's role in cellular health and potentially telomere support.

  6. Spermidine (Wheat Germ Concentrate)

    Longevity & Autophagy · 1–6 mg spermidine

    Promotes autophagy, a cellular cleanup process that removes damaged components and can contribute to cellular rejuvenation and longevity.

  7. Urolithin A (Mitophagy)

    Longevity & Mitochondrial · 500 mg

    Enhances mitophagy, the selective removal of damaged mitochondria, supporting cellular energy production and overall cellular health.

  8. Cycloastragenol

    Longevity & NAD+ · 5 mg

    A derivative of astragalus, specifically researched for its potential to support telomere length and cellular vitality.

  9. NMN High Dose (1 g)

    Longevity & NAD+ · 1000 mg

    Boosts NAD+ levels, crucial for cellular energy metabolism and DNA repair mechanisms that are vital for maintaining cellular health.

  10. Alpha-Ketoglutarate Pure

    Epigenetic Longevity · 500 mg

    A key metabolite involved in cellular energy and epigenetic regulation, supporting cellular function and potentially longevity pathways.

Ready to build your stack?

4–8 weeks to feel the full benefit. Start with MES if you're new — that's where most people land.

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