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DIM High Dose (3,3'-Diindolylmethane) — SacredBod supplement bottle (illustrative)
Supplement · Estrogen Metabolism & Detox

DIM High Dose (3,3'-Diindolylmethane)

300 mg · vegan · gluten-free · 60 caps

hormonal imbalanceskin-breakoutspms liveradrenal glandthyroid gland
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Overview Stacks Timing Related FAQs Blog

What it is

DIM High Dose (3,3'-Diindolylmethane) is a estrogen metabolism & detox supplement. High-dose DIM (3,3'-diindolylmethane) is the active cruciferous metabolite that steers estrogen metabolism toward protective pathways. Used in adult dosing protocols in India and internationally, it is sold as a single-ingredient supplement.

How it works

DIM promotes 2-hydroxylation of estrogens over 16-hydroxylation, favouring weaker, protective metabolites and supporting phase-I/II detox of hormones. Effects are dose-dependent and typically measurable within 4-12 weeks.

Who should take it

Adults with estrogen-dominance symptoms, hormonal acne or PMS seeking metabolite balance.

Avoid / careful

Pregnancy and hormone-sensitive cancers. May alter hormonal-medication levels. Can colour urine (harmless).

When to take it

Morning
Noon
Evening
Night

How to take it

With food
Empty stomach
Before food

FAQs

Frequently asked

What is the difference between DIM and I3C?
DIM (3,3'-Diindolylmethane) is a stable, direct metabolite of Indole-3-Carbinol (I3C), which is found in cruciferous vegetables. DIM is generally preferred in supplements due to its stability and more predictable effects on estrogen metabolism compared to I3C, which requires stomach acid to convert into DIM and other compounds.
How long does it take to see results with DIM High Dose?
While individual responses vary, most users typically begin to notice improvements in symptoms and measurable changes in estrogen metabolite ratios within 4 to 12 weeks of consistent daily use. Optimal results are often seen with continued use over several months.
Can DIM High Dose be taken with other supplements?
DIM High Dose can generally be taken with most other supplements. However, if you are taking other hormone-modulating supplements or medications, it is advisable to consult with a healthcare professional to ensure there are no potential interactions or contraindications.

From the blog

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DIM High Dose (3,3'-Diindolylmethane) Dosage: How Much Should You Take?

How much DIM High Dose (3,3'-Diindolylmethane) to take, when to take it, which form is best, and how to stack it safely.

#dosage#how-to#estrogen
· 8 min read

Top Benefits of DIM High Dose (3,3'-Diindolylmethane) (Evidence-Based)

The science-backed benefits of DIM High Dose (3,3'-Diindolylmethane), the mechanisms behind them, and how to know if it is working for you.

#benefits#evidence#estrogen
· 8 min read

What Is DIM High Dose (3,3'-Diindolylmethane)? A Complete India Guide

A complete guide to DIM High Dose (3,3'-Diindolylmethane): what it is, how it works, benefits, dosing, safety and where to buy it in India.

#guide#india#estrogen

Editorial notes

SacredBod's longer take on DIM High Dose (3,3'-Diindolylmethane) — context the structured blocks above don't capture.

About DIM High Dose (3,3’-Diindolylmethane)

High-dose DIM for healthy estrogen metabolism and hormonal acne support..

How it works

DIM promotes 2-hydroxylation of estrogens over 16-hydroxylation, favouring weaker, protective metabolites and supporting phase-I/II detox of hormones. Effects are dose-dependent and typically measurable within 4-12 weeks.

Who it’s for

Adults with estrogen-dominance symptoms, hormonal acne or PMS seeking metabolite balance.

Dosage & timing

  • Typical dose: 300 mg
  • Best time: morning
  • With food: with-food
  • Expected onset: 4-12 weeks.

Safety

Pregnancy and hormone-sensitive cancers. May alter hormonal-medication levels. Can colour urine (harmless).

Added to your stack.