Angelica sinensis · Dang Gui · Female Ginseng
500 mg · vegan · gluten-free · 60 caps
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Angelica sinensis is one of the most widely used women's herbs in TCM, traditionally prescribed for menstrual irregularities, menopausal symptoms, and blood deficiency. Despite its popularity, modern clinical evidence is inconsistent and often negative for primary menopausal endpoints.
Dong quai contains ferulic acid and polysaccharides with weak estrogenic activity in vitro, but human studies have failed to show consistent effects on hot flashes, vaginal atrophy, or hormone levels. Some formulations (like Climex, combined with chamomile) show modest benefit, suggesting synergy with other herbs may be necessary.
Adult women exploring TCM approaches for menstrual or menopausal symptoms. Not a substitute for hormone replacement therapy or medical evaluation for abnormal bleeding.
Avoid during pregnancy, breastfeeding, or if you have hormone-sensitive conditions (breast cancer, endometriosis, uterine fibroids). May increase bleeding risk—discontinue 2 weeks before surgery. Contains coumarins—caution with warfarin.
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✓ Split doses to maintain steady blood levels
✓ Split doses to maintain steady blood levels
✓ Take with food to reduce digestive upset and improve absorption
Dong quai contains ferulic acid and polysaccharides with weak estrogenic activity in vitro, but human studies have failed to show consistent effects on hot flashes, vaginal atrophy, or hormone levels.
Each bar = one cited trial. Effect varies by methodology, dose, and population.
Representative cohort from published RCT data
Relative to baseline (100). Data from published clinical literature.
55 postmenopausal women
→ Modest reduction in hot flush frequency versus placebo after 12 weeks; effect size was small
20 men
→ No significant difference from placebo for hot flash frequency or severity; study terminated early
Review
→ No data on safety in breastfeeding; coumarin content raises theoretical bleeding concerns
C · Weak and inconsistent evidence for menopausal symptoms. A negative RCT in men with hot flashes and modest results only in combination formulas. Traditional use vastly exceeds modern clinical validation.
A plain-English read of the literature behind this supplement. Not a clinical recommendation.
Key citations: See richResearch section for study filters and participant data. Clinical evidence summarised from peer-reviewed journals.
How to use Dong Quai specifically for Hot flashes — the right dose, timing, blood markers to track, and how to know if it is working.
A clinical evidence review of Dong Quai — RCT data, effect sizes, evidence grade, and what the numbers mean for your specific situation.
Everything you need to know about Dong Quai — mechanism, dose, safety, buying guide for India, and what the research actually says.
SacredBod's longer take on Dong Quai — context the structured blocks above don't capture.
Angelica sinensis is one of the most widely used women’s herbs in TCM, traditionally prescribed for menstrual irregularities, menopausal symptoms, and blood deficiency. Despite its popularity, modern clinical evidence is inconsistent and often negative for primary menopausal endpoints.
Dong quai contains ferulic acid and polysaccharides with weak estrogenic activity in vitro, but human studies have failed to show consistent effects on hot flashes, vaginal atrophy, or hormone levels. Some formulations (like Climex, combined with chamomile) show modest benefit, suggesting synergy with other herbs may be necessary.
Who benefits most
Adult women exploring TCM approaches for menstrual or menopausal symptoms. Not a substitute for hormone replacement therapy or medical evaluation for abnormal bleeding.
Dosage and form
500 mg is the typical effective range. Forms matter: choose standardised extracts or highly bioavailable delivery formats (see the Forms tab). Take as directed.
Side effects and cautions
Photosensitivity at high doses. Pregnancy contraindicated. Avoid if you: Avoid during pregnancy, breastfeeding, or if you have hormone-sensitive conditions (breast cancer, endometriosis, uterine fibroids). May increase bleeding risk—discontinue 2 weeks before surgery. Contains coumarins—caution with warfarin..
The evidence
Human clinical trials and mechanistic research support the use of Dong Quai for its primary indication. See the Research tab for full citations and study summaries.
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