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Fisetin High Dose (500 mg) — SacredBod supplement bottle (illustrative)
Supplement · Longevity & Senolytic

Fisetin High Dose (500 mg)

500 mg · vegan · gluten-free · 60 caps

premature-aginginflammation connective tissueimmune system
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What it is

Fisetin High Dose (500 mg) is a longevity & senolytic supplement. High-dose fisetin is a flavonoid taken at senolytic levels to target senescent ('zombie') cells. Used in adult dosing protocols in India and internationally, it is sold as a single-ingredient supplement.

How it works

At high doses fisetin selectively triggers apoptosis in senescent cells (senolysis) and reduces the inflammatory SASP, alongside broad antioxidant action. Effects are dose-dependent and typically measurable within cyclic senolytic dosing.

Who should take it

Adults exploring senolytic protocols for healthy ageing and inflammation.

Avoid / careful

Often used in short cyclic 'hit-and-run' protocols. Mild antiplatelet effect. Limited long-term data; consult a clinician.

When to take it

Morning
Noon
Evening
Night

How to take it

With food
Empty stomach
Before food

FAQs

Frequently asked

What are senescent cells?
Senescent cells are aged cells that stop dividing but remain metabolically active, often secreting inflammatory molecules that can damage surrounding tissues.
How does fisetin clear senescent cells?
Fisetin triggers apoptosis (programmed cell death) specifically in senescent cells, effectively removing them from tissues.
Is fisetin safe for long-term daily use?
Current research often focuses on cyclic 'hit-and-run' protocols. Long-term daily use data is limited, and it's advisable to consult a healthcare professional.

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Editorial notes

SacredBod's longer take on Fisetin High Dose (500 mg) — context the structured blocks above don't capture.

About Fisetin High Dose (500 mg)

Senolytic-dose fisetin flavonoid to clear senescent cells..

How it works

At high doses fisetin selectively triggers apoptosis in senescent cells (senolysis) and reduces the inflammatory SASP, alongside broad antioxidant action. Effects are dose-dependent and typically measurable within cyclic senolytic dosing.

Who it’s for

Adults exploring senolytic protocols for healthy ageing and inflammation.

Dosage & timing

  • Typical dose: 500 mg
  • Best time: morning
  • With food: with-food
  • Expected onset: Cyclic senolytic dosing.

Safety

Often used in short cyclic ‘hit-and-run’ protocols. Mild antiplatelet effect. Limited long-term data; consult a clinician.

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