Astragalus membranaceus · Huang Qi · Milk Vetch
1000 mg · vegan · gluten-free · 60 caps
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Astragalus membranaceus is a foundational TCM Qi tonic used for immune resilience and respiratory health. Its active polysaccharides stimulate immune cell activity, and it has been traditionally used for chronic cough, weakness, and recurrent infections. The evidence base is strong in animal models but limited in human respiratory trials.
Astragalus polysaccharides interact with TLR4 receptors on macrophages and dendritic cells, stimulating cytokine production, natural killer cell activity, and T-cell proliferation. Saponins (astragalosides) may support mitochondrial function. For respiratory outcomes, the herb is thought to enhance mucosal immunity and reduce susceptibility to viral and bacterial infections.
Adults with frequent respiratory infections or recovering from viral illness. Not a replacement for vaccines, antibiotics when indicated, or medical treatment of pneumonia or COPD.
Avoid if you have autoimmune conditions (may stimulate immune activity). Use caution with immunosuppressant medications. No safety data for pregnancy or breastfeeding.
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✓ Morning for energy and immune activation; evening for recovery during sleep
✓ Morning for energy and immune activation; evening for recovery during sleep
✓ Take with meals to improve absorption and reduce stomach upset
Astragalus polysaccharides interact with TLR4 receptors on macrophages and dendritic cells, stimulating cytokine production, natural killer cell activity, and T-cell proliferation.
Each bar = one cited trial. Effect varies by methodology, dose, and population.
Healthy adults cohort over 6 months (n≈80)
Average upper respiratory infections in control group: 2.0/month.
In vitro
→ Astragalus polysaccharides bind to TLR4 on macrophages, triggering immune activation cascades
Rat model
→ Combined astragalus polysaccharides and schisandra lignans significantly reduced liver enzyme elevation and oxidative stress
Animal model
→ Enhanced immune gene expression and disease resistance; note this is an aquatic animal study, not human
B · Strong mechanistic and animal data for immune modulation. Human clinical trials for respiratory outcomes are small, heterogeneous, and often of low methodological quality. No large RCTs for preventing respiratory infections in healthy adults.
A plain-English read of the literature behind this supplement. Not a clinical recommendation.
Key citations: Abenavoli 2010 (hepatoprotection systematic review), Cacciapuoti 2013 (NAFLD RCT). richResearch section contains study filters.
How to use Astragalus (Respiratory) specifically for Frequent respiratory infections — the right dose, timing, blood markers to track, and how to know if it is working.
A clinical evidence review of Astragalus (Respiratory) — RCT data, effect sizes, evidence grade, and what the numbers mean for your specific situation.
Everything you need to know about Astragalus (Respiratory) — mechanism, dose, safety, buying guide for India, and what the research actually says.
SacredBod's longer take on Astragalus (Respiratory) — context the structured blocks above don't capture.
Astragalus membranaceus is a foundational TCM Qi tonic used for immune resilience and respiratory health. Its active polysaccharides stimulate immune cell activity, and it has been traditionally used for chronic cough, weakness, and recurrent infections. The evidence base is strong in animal models but limited in human respiratory trials.
Astragalus polysaccharides interact with TLR4 receptors on macrophages and dendritic cells, stimulating cytokine production, natural killer cell activity, and T-cell proliferation. Saponins (astragalosides) may support mitochondrial function. For respiratory outcomes, the herb is thought to enhance mucosal immunity and reduce susceptibility to viral and bacterial infections.
Who benefits most
Adults with frequent respiratory infections or recovering from viral illness. Not a replacement for vaccines, antibiotics when indicated, or medical treatment of pneumonia or COPD.
Dosage and form
1000 mg is the typical effective range. Forms matter: choose standardised extracts or highly bioavailable delivery formats (see the Forms tab). Take as directed.
Side effects and cautions
Generally well-tolerated. Avoid if you: Avoid if you have autoimmune conditions (may stimulate immune activity). Use caution with immunosuppressant medications. No safety data for pregnancy or breastfeeding..
The evidence
Human clinical trials and mechanistic research support the use of Astragalus (Respiratory) for its primary indication. See the Research tab for full citations and study summaries.
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