GSE · OPC · Oligomeric proanthocyanidins · Pycnogenol-like
150 mg · vegan · gluten-free · 60 caps
Affiliate link · we earn from qualifying purchases. No paid placements.
Concentrated extract of Vitis vinifera grape seeds, standardized to oligomeric proanthocyanidins (OPCs). Same class of polyphenols as pine bark extract (Pycnogenol) but from a different source. Standardization can range from 30% to 95% OPC content — the higher the better for clinical effect.
OPCs are powerful antioxidants that strengthen capillaries, reduce LDL oxidation, and may modulate endothelial function. The vascular protective effect drives the BP-lowering observed in trials (typically 5-6 mmHg systolic reduction).
Adults with mild hypertension or capillary fragility (easy bruising). Diabetic adults concerned about microvascular complications.
Concurrent anticoagulants (theoretical bleeding risk). Major surgery (stop 2 weeks before). Iron-deficient adults — high-tannin extracts may impair iron absorption when taken with meals.
Pick a depth — minimum to maximal coverage
No full stack configured.
Click individual supplement pills above to buy each on Amazon India.
✓ Morning or split dose
✓ Improves absorption and reduces GI discomfort
OPCs are powerful antioxidants that strengthen capillaries, reduce LDL oxidation, and may modulate endothelial function.
Each bar = one cited trial. Effect varies by methodology, dose, and population.
Stage 1 hypertension cohort (n≈70)
Target systolic BP <130 mmHg (ACC/AHA 2017 guidelines).
B · Meta-analyses show modest BP reduction. Most marketing claims (cancer, anti-aging) are mechanistic, not from outcome trials.
A plain-English read of the literature behind this supplement. Not a clinical recommendation.
Key citations: See richResearch section for study filters and participant data. Clinical evidence summarised from peer-reviewed journals.
How to use Grape Seed Extract specifically for Mild hypertension — the right dose, timing, blood markers to track, and how to know if it is working.
A clinical evidence review of Grape Seed Extract — RCT data, effect sizes, evidence grade, and what the numbers mean for your specific situation.
Everything you need to know about Grape Seed Extract — mechanism, dose, safety, buying guide for India, and what the research actually says.
SacredBod's longer take on Grape Seed Extract — context the structured blocks above don't capture.
Concentrated extract of Vitis vinifera grape seeds, standardized to oligomeric proanthocyanidins (OPCs). Same class of polyphenols as pine bark extract (Pycnogenol) but from a different source. Standardization can range from 30% to 95% OPC content — the higher the better for clinical effect.
OPCs are powerful antioxidants that strengthen capillaries, reduce LDL oxidation, and may modulate endothelial function. The vascular protective effect drives the BP-lowering observed in trials (typically 5-6 mmHg systolic reduction).
The evidence base (B- grade) reflects this: Meta-analyses show modest BP reduction. Most marketing claims (cancer, anti-aging) are mechanistic, not from outcome trials. For practical use, the typical dose range is 150-300 mg standardized OPC daily, ideally with a fat-containing meal for fat-soluble compounds.
Who benefits most: Adults with mild hypertension or capillary fragility (easy bruising). Diabetic adults concerned about microvascular complications.
Cautions: Concurrent anticoagulants (theoretical bleeding risk). Major surgery (stop 2 weeks before). Iron-deficient adults — high-tannin extracts may impair iron absorption when taken with meals.
Pairing notes: Vitamin C for collagen synergy. Quercetin for combined flavonoids.
Peptides are physician-only. Tell us a bit and we'll route you to the right specialist.
