Pycnogenol · French Maritime Pine Bark · Proanthocyanidins
100–200 mg Pycnogenol · vegan · gluten-free · 60 caps
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Pine bark extract refers to preparations from the bark of *Pinus pinaster* (French maritime pine). The best-studied branded extract is Pycnogenol®, standardized to 70–75% procyanidins. Generic "pine bark extract" products without standardization may not replicate the clinical trial data. This is an important distinction: most RCT evidence is Pycnogenol-specific.
Proanthocyanidins improve endothelial nitric oxide production, reduce capillary permeability, and scavenge free radicals. In chronic venous insufficiency (CVI), this reduces leg edema and improves venous tone. In diabetes, modest blood-pressure reductions have been observed, likely via improved vascular relaxation. The ADHD trial suggested small improvements in attention, possibly via antioxidant effects in neural tissue and mild reductions in oxidative stress markers.
Adults with chronic venous insufficiency symptoms, mild hypertension, or those seeking vascular antioxidant support. People with ADHD should not self-medicate with pine bark; the trial data is exploratory and industry-funded.
Avoid if you have autoimmune conditions (theoretical immunomodulation concern), or if you take anticoagulants or antiplatelet drugs without physician guidance. Not recommended during pregnancy or breastfeeding due to insufficient safety data.
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Click individual supplement pills above to buy each on Amazon India.
✓ Split dosing improves sustained vascular coverage.
✓ Split dosing improves sustained vascular coverage.
✓ Take with meals to improve absorption of lipid-soluble procyanidins.
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Each bar = one cited trial. Effect varies by methodology, dose, and population.
Representative cohort from published RCT data
Relative to baseline (100). Data from published clinical literature.
see study
→ Meta-review of Pycnogenol trials showing reduced leg edema, improved venous ulcer healing, and lower DVT risk in long-haul travel.
see study
→ Modest reductions in systolic BP and LDL oxidation in type 2 diabetes patients over 12 weeks.
see study
→ Small RCT in children showed reduced hyperactivity and improved attention after 1 month; effect size modest and industry-funded.
A plain-English read of the literature behind this supplement. Not a clinical recommendation.
Key citations: See richResearch section. Multiple RCTs support cognitive and neuroprotective properties of Pine Bark Extract.
How to use Pine Bark Extract specifically for leg swelling — the right dose, timing, blood markers to track, and how to know if it is working.
A clinical evidence review of Pine Bark Extract — RCT data, effect sizes, evidence grade, and what the numbers mean for your specific situation.
Everything you need to know about Pine Bark Extract — mechanism, dose, safety, buying guide for India, and what the research actually says.
SacredBod's longer take on Pine Bark Extract — context the structured blocks above don't capture.
Pycnogenol® has reasonable small-trial evidence for chronic venous insufficiency—reducing leg swelling and improving venous tone. The blood-pressure and ADHD data are more preliminary. Most of the positive literature is industry-funded, which does not invalidate the findings but means independent replication is limited. Generic pine bark extracts without standardization to 70–75% procyanidins cannot claim the same evidence base. If you have significant venous disease, see a vascular specialist; supplements are adjuncts, not replacements for compression stockings or medical therapy.
Take 100 mg with breakfast and 100 mg with dinner. Use a Pycnogenol®-standardized product. Reassess after 8–12 weeks if venous symptoms have not improved.
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