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Indole-3-Carbinol (High Dose) — SacredBod supplement bottle (illustrative)
Supplement · Estrogen Metabolism

Indole-3-Carbinol (High Dose)

400 mg · vegan · gluten-free · 60 caps

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What it is

Indole-3-Carbinol (High Dose) is a estrogen metabolism supplement. Indole-3-carbinol is the cruciferous-vegetable precursor that converts in the stomach to DIM and related oligomers. Used in adult dosing protocols in India and internationally, it is sold as a single-ingredient supplement.

How it works

I3C and its acid condensation products upregulate phase-I/II detox enzymes and favour the 2-hydroxyoestrone pathway, supporting healthy oestrogen metabolism. Effects are dose-dependent and typically measurable within 4-12 weeks.

Who should take it

Adults seeking cruciferous-derived oestrogen-metabolism and detox support.

Avoid / careful

Pregnancy and hormone-sensitive conditions. High doses may cause GI upset; DIM is often preferred for consistency.

When to take it

Morning
Noon
Evening
Night

How to take it

With food
Empty stomach
Before food

FAQs

Frequently asked

What is the difference between Indole-3-Carbinol and DIM?
Indole-3-Carbinol (I3C) is the precursor found in cruciferous vegetables. In the stomach's acidic environment, it converts into DIM and other oligomers. DIM is often used directly as it offers more consistent absorption and predictable effects.
Can high doses of I3C cause side effects?
Yes, high doses of I3C can potentially lead to gastrointestinal upset, such as nausea or bloating, in some individuals. Starting with a lower dose or opting for DIM may mitigate these effects.
How long does it take to see results from high-dose I3C?
The effects of high-dose Indole-3-Carbinol are dose-dependent and typically become measurable within 4 to 12 weeks of consistent daily use.

From the blog

· 8 min read

Indole-3-Carbinol (High Dose) Dosage: How Much Should You Take?

How much Indole-3-Carbinol (High Dose) to take, when to take it, which form is best, and how to stack it safely.

#dosage#how-to#estrogen
· 8 min read

Top Benefits of Indole-3-Carbinol (High Dose) (Evidence-Based)

The science-backed benefits of Indole-3-Carbinol (High Dose), the mechanisms behind them, and how to know if it is working for you.

#benefits#evidence#estrogen
· 8 min read

What Is Indole-3-Carbinol (High Dose)? A Complete India Guide

A complete guide to Indole-3-Carbinol (High Dose): what it is, how it works, benefits, dosing, safety and where to buy it in India.

#guide#india#estrogen

Editorial notes

SacredBod's longer take on Indole-3-Carbinol (High Dose) — context the structured blocks above don't capture.

About Indole-3-Carbinol (High Dose)

High-dose I3C from cruciferous vegetables for oestrogen-metabolite balance..

How it works

I3C and its acid condensation products upregulate phase-I/II detox enzymes and favour the 2-hydroxyoestrone pathway, supporting healthy oestrogen metabolism. Effects are dose-dependent and typically measurable within 4-12 weeks.

Who it’s for

Adults seeking cruciferous-derived oestrogen-metabolism and detox support.

Dosage & timing

  • Typical dose: 400 mg
  • Best time: morning
  • With food: with-food
  • Expected onset: 4-12 weeks.

Safety

Pregnancy and hormone-sensitive conditions. High doses may cause GI upset; DIM is often preferred for consistency.

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