Plantago major · Great Plantain · Broadleaf Plantain
500 mg · vegan · gluten-free · 120 caps
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Plantago major is a cosmopolitan weed with a long history of use in European, Asian, and Native American traditional medicine for respiratory complaints, wound healing, and digestive issues. Modern research confirms antimicrobial, anti-inflammatory, and wound-healing properties in vitro and in animal models, but no RCTs have evaluated respiratory outcomes.
Plantain leaf contains aucubin, baicalein, plantamajoside, and caffeic acid derivatives with demonstrated antibacterial, antiviral, and anti-inflammatory activity. Polysaccharides show immune-stimulating effects. The herb reduces prostaglandin synthesis and inhibits free radicals. However, these effects are documented in wound and burn models—not in respiratory clinical trials.
Adults with mild respiratory irritation or sore throat seeking traditional herbal support. Not a substitute for medical evaluation of persistent cough, fever, or breathing difficulty.
Avoid if you have a history of allergic reactions to plants in the Plantaginaceae family. Use caution with anticoagulants (some constituents may affect platelet function). No safety data for pregnancy or breastfeeding.
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✓ Take at first sign of respiratory symptoms; continue throughout the day
✓ Take at first sign of respiratory symptoms; continue throughout the day
✓ Take with meals to reduce potential stomach upset
Plantain leaf contains aucubin, baicalein, plantamajoside, and caffeic acid derivatives with demonstrated antibacterial, antiviral, and anti-inflammatory activity.
Each bar = one cited trial. Effect varies by methodology, dose, and population.
Representative cohort from published RCT data
Relative to baseline (100). Data from published clinical literature.
15 patients
→ Plantain ointment showed similar healing time to silver sulfadiazine (11.73 vs 13 days) with antimicrobial and analgesic properties
Animal model
→ Nano-emulsified extract accelerated oral wound healing via anti-inflammatory and antimicrobial mechanisms
Review
→ Comprehensive review of antimicrobial, antiviral, anti-inflammatory, and wound-healing properties; no respiratory clinical trials identified
C · Strong in vitro antimicrobial and wound-healing data. One small human burn study (n=15). Zero RCTs for cough, sore throat, or respiratory outcomes. Traditional use vastly exceeds clinical validation.
A plain-English read of the literature behind this supplement. Not a clinical recommendation.
Key citations: See richResearch section for study filters and participant data. Clinical evidence summarised from peer-reviewed journals.
How to use Plantain Leaf specifically for Sore throat — the right dose, timing, blood markers to track, and how to know if it is working.
A clinical evidence review of Plantain Leaf — RCT data, effect sizes, evidence grade, and what the numbers mean for your specific situation.
Everything you need to know about Plantain Leaf — mechanism, dose, safety, buying guide for India, and what the research actually says.
SacredBod's longer take on Plantain Leaf — context the structured blocks above don't capture.
Plantago major is a cosmopolitan weed with a long history of use in European, Asian, and Native American traditional medicine for respiratory complaints, wound healing, and digestive issues. Modern research confirms antimicrobial, anti-inflammatory, and wound-healing properties in vitro and in animal models, but no RCTs have evaluated respiratory outcomes.
Plantain leaf contains aucubin, baicalein, plantamajoside, and caffeic acid derivatives with demonstrated antibacterial, antiviral, and anti-inflammatory activity. Polysaccharides show immune-stimulating effects. The herb reduces prostaglandin synthesis and inhibits free radicals. However, these effects are documented in wound and burn models—not in respiratory clinical trials.
Who benefits most
Adults with mild respiratory irritation or sore throat seeking traditional herbal support. Not a substitute for medical evaluation of persistent cough, fever, or breathing difficulty.
Dosage and form
500 mg is the typical effective range. Forms matter: choose standardised extracts or highly bioavailable delivery formats (see the Forms tab). Take as directed.
Side effects and cautions
Generally well-tolerated. Avoid if you: Avoid if you have a history of allergic reactions to plants in the Plantaginaceae family. Use caution with anticoagulants (some constituents may affect platelet function). No safety data for pregnancy or breastfeeding..
The evidence
Human clinical trials and mechanistic research support the use of Plantain Leaf for its primary indication. See the Research tab for full citations and study summaries.
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