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Autoimmune Support Protocol supplement stack (illustrative)
Stack · Immune Advanced Protocols

Autoimmune Support Protocol

Modulating immune response and reducing inflammation.

Autoimmune flare-upsChronic inflammationImmune dysregulationFatigue
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Quick facts
  • 10 supplements
  • Evidence: C
  • 1/5/10 tier picker

Pick your depth

Same stack, three commitment levels.

FULL
10 supplements · max coverage
Curcumin BCM-95 PainPalmitoylethanolamide (PEA)Omega-3 Fish OilAstragalus (Huang Qi)AndrographisDuanwood Red ReishiZinc PicolinateAKBA Boswellic AcidAstragalus Polysaccharide APSKalonji (Black Seed)
BUY Curcumin BCM-95 Pain → BUY Palmitoylethanolamide (PEA) → BUY Omega-3 Fish Oil → BUY Astragalus (Huang Qi) → BUY Andrographis → BUY Duanwood Red Reishi → BUY Zinc Picolinate → BUY AKBA Boswellic Acid → BUY Astragalus Polysaccharide APS → BUY Kalonji (Black Seed) →
Overview Symptoms & markers

Aims to support a balanced immune response and reduce chronic inflammation associated with autoimmune conditions.

What it's for

This stack includes immune-modulating herbs like Astragalus and medicinal mushrooms, alongside anti-inflammatory agents like Curcumin and Omega-3s, to help regulate the immune system.

Not for:This is not a cure for autoimmune diseases and should not replace medical treatment. Consult your doctor.

Symptoms it can address

✓ Autoimmune flare-ups✓ Chronic inflammation✓ Immune dysregulation✓ Fatigue
Evidence grade
ABCD

C · Pooled evidence for the stack as a whole. Individual supplements may have stronger or weaker grades — see their pages.

Members of the FULL stack

  1. Curcumin BCM-95 Pain

    Natural Pain Management · 500 mg

    Potent anti-inflammatory, specifically targets inflammation pathways relevant to autoimmune conditions and pain reduction.

    Details BUY →

  2. Palmitoylethanolamide (PEA)

    Lipid · 400 mg

    Endogenous lipid that modulates immune cells and reduces neuroinflammation, complementary to curcumin's anti-inflammatory action.

    Details BUY →

  3. Omega-3 Fish Oil

    Fatty Acid · 1,000 mg EPA+DHA

    Provides EPA and DHA, crucial fatty acids that help suppress inflammatory cytokines and support immune balance.

    Details BUY →

  4. Astragalus (Huang Qi)

    Adaptogen · 500 mg

    Key TCM herb for immune modulation, helping to regulate immune responses and support overall immune function.

    Details BUY →

  5. Andrographis

    Herb · 500 mg

    Potent adaptogen with strong anti-inflammatory and immune-modulating properties, useful for acute immune challenges.

    Details BUY →

  6. Duanwood Red Reishi

    Mushroom · 1000 mg

    Medicinal mushroom known for its immunomodulatory and anti-inflammatory benefits, supporting a balanced immune system.

    Details BUY →

  7. Zinc Picolinate

    Mineral (Zinc Form) · 22 mg

    Essential mineral for immune cell function and regulation, helps maintain immune homeostasis and reduce inflammation.

    Details BUY →

  8. AKBA Boswellic Acid

    Advanced Anti-Inflammatory · 100 mg

    Highly bioavailable form of Boswellia serrata, potent anti-inflammatory targeting pathways like 5-LOX.

    Details BUY →

  9. Astragalus Polysaccharide APS

    Immune Advanced Protocols · 500 mg–2 g

    Specific Astragalus extract focusing on polysaccharides, known for their immune-stimulating and regulatory effects.

    Details BUY →

  10. Kalonji (Black Seed)

    Herb · 500 mg

    Traditional Ayurvedic herb with broad anti-inflammatory and immune-modulating effects, supporting overall immune health.

    Details BUY →

Ready to build your stack?

4–8 weeks to feel the full benefit. Start with MES if you're new — that's where most people land.

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