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Deep Rest Sleep Optimisation supplement stack (illustrative)
Stack · Sleep Optimisation Protocols

Deep Rest Sleep Optimisation

Enhancing sleep quality for profound rest and recovery.

Difficulty staying asleepNon-restorative sleepWaking frequentlyDaytime fatigue
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Quick facts
  • 10 supplements
  • Evidence: B
  • 1/5/10 tier picker

Pick your depth

Same stack, three commitment levels.

FULL
10 supplements · max coverage
Magnesium GlycinateApigeninValerian + Hops ComboPassion Flower ExtractAshwagandha KSM-66 (Sleep)Jujube Seed ExtractMagnolia Bark (Honokiol)L-TryptophanMelatoninHops Extract (Humulus Lupulus)
BUY Magnesium Glycinate → BUY Apigenin → BUY Valerian + Hops Combo → BUY Passion Flower Extract → BUY Ashwagandha KSM-66 (Sleep) → BUY Jujube Seed Extract → BUY Magnolia Bark (Honokiol) → BUY L-Tryptophan → BUY Melatonin → BUY Hops Extract (Humulus Lupulus) →
Overview Symptoms & markers

Focuses on promoting deeper sleep cycles and improving sleep efficiency for enhanced physical and mental recovery.

What it's for

This stack combines calming herbs like Valerian and Passionflower with sleep-supportive nutrients like Magnesium Glycinate and Apigenin to promote relaxation and deeper sleep.

Not for:This is not a treatment for insomnia caused by underlying medical conditions. Consult your doctor.

Symptoms it can address

✓ Difficulty staying asleep✓ Non-restorative sleep✓ Waking frequently✓ Daytime fatigue
Evidence grade
ABCD

B · Pooled evidence for the stack as a whole. Individual supplements may have stronger or weaker grades — see their pages.

Members of the FULL stack

  1. Magnesium Glycinate

    Mineral · 200 mg

    Promotes relaxation and supports deeper sleep by providing bioavailable magnesium, crucial for neurotransmitter function.

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  2. Apigenin

    Botanical · 50 mg

    A flavonoid that binds to GABA receptors, promoting calmness and reducing sleep onset latency for profound rest.

    Details BUY →

  3. Valerian + Hops Combo

    Sleep Support · 500 mg valerian + 120 mg hops

    Combines Valerian root and Hops extract to synergistically enhance GABAergic activity, facilitating relaxation and sleep initiation.

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  4. Passion Flower Extract

    sleep · 300-500 mg extract (or 1-2 g dried herb)

    Calms the nervous system and reduces anxiety with flavonoids, supporting a smoother transition into restful sleep.

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  5. Ashwagandha KSM-66 (Sleep)

    Adaptogen & Sleep · 600 mg KSM-66

    An adaptogen that helps manage stress and promotes relaxation, contributing to improved sleep quality and recovery.

    Details BUY →

  6. Jujube Seed Extract

    sleep · 500-1,000 mg extract (or 9-15 g dried seed decoction)

    A TCM herb known for its calming properties, helping to soothe the mind and prepare the body for deep, restorative sleep.

    Details BUY →

  7. Magnolia Bark (Honokiol)

    Sleep & Stress · 250 mg

    Contains honokiol, which interacts with GABA receptors to promote relaxation and reduce anxiety, aiding in deeper sleep.

    Details BUY →

  8. L-Tryptophan

    sleep · 500 mg – 2 g before bed

    A precursor to serotonin and melatonin, essential for regulating sleep-wake cycles and promoting a sense of well-being.

    Details BUY →

  9. Melatonin

    Hormone · 0.3 mg

    A hormone that helps regulate the body's natural sleep-wake cycle, signaling to the body that it's time to rest.

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  10. Hops Extract (Humulus Lupulus)

    Sleep & GABAergic · 120–300 mg

    Contains compounds that bind to GABA receptors, contributing to sedative effects and enhancing sleep quality.

    Details BUY →

Ready to build your stack?

4–8 weeks to feel the full benefit. Start with MES if you're new — that's where most people land.

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